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Latent Space

🔬 Training Transformers to solve 95% failure rate of Cancer Trials — Ron Alfa & Daniel Bear, Noetik

April 20, 20261h 25m · 15,009 words

Show notes

Today, we explain this piece of “clickbait” from our guest! TL;DR: 95% of cancer treatments fail to pass clinical trials, but it may be a matching problem — if we better understood what patients have which tumors which will respond to which treatments, success rates improve dramatically and millions of lives can be saved — with the treatments we ALREADY have.

Highlighted moments

So you can think of one of those data points as an image, except instead of being an RGB image that has three color channels. Now, all of a sudden it has like 20,000 colors.
you only really see the benefits of using larger models when you're looking at longer context lengths. And here, longer context really means, again, like you're seeing more tissue at once, more area at once.
it doesn't follow that, like, any data set is a machine learning data set. It doesn't follow that that data set is going to solve the problem you're trying to solve.
my bet is that the same is going to be true for these models too is that, like, by modeling sort of at the level of functional tissue where you have a bunch of cells interacting in, like, a disease context that that's going to get you to the problem of predicting kind of the patient-level behavior much faster than trying to first model a cell and then stitch a bunch of those cells together.

Transcript

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