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Let's Talk Chemistry- a science podcast by ChemTalk

Episode 58: Nobel Laureate Dr. Benjamin List on Organocatalysis

August 22, 202524 min · 4,246 words

Show notes

Nobel laureate Dr. Benjamin List is one of the directors of the Max Planck Institute for Coal Research and professor of organic chemistry at the University of Cologne. On top of that, he is known for pioneering a brand new field of chemistry, organocatalysis, which is now used in nearly all pharmaceutical industries.

Highlighted moments

what impressed me, I think, was sort of this predictableness about chemistry, right? You could predict if you mixed, you know, liquid A with solid B, another colorful material will precipitate. And in a reproducible and predictable way.
That's where then the magic comes, because it means that one capitalist molecule in principle can do its job an infinite number of times. And that's also where the economic fascination comes from, because it means a small amount of something, a capitalist, can create a huge amount of something else that might be valuable.
my observation was when I was a postdoc at Scripps that the fascinating thing about biocatalysts, about these enzymes, is that sometimes they do have a nectar, but sometimes they don't. And chemists, in contrast, believe they would always need a metal in their catalytic molecules. And that was the starting point for this question, can we also use organic catalysts?

Transcript

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