
Masterminds and Mindware for Agentic AI: Contextualized and Applied
January 29, 202627 min · 4,577 words
Show notes
Agentic AI is moving beyond assistive tools toward systems that can reason, plan, and act within complex workflows. In the latest episode of the Harvard Data Science Review Podcast, we speak with Dirk Hofmann and Ulla Kruhse-Lehtonen, co-founders and co-CEOs of DAIN Studios, about what this shift means for organizations in practice. The conversation explores how agentic AI differs from traditional automation, why outcomes matter more than outputs, and how humans and AI agents can work together responsibly. Drawing on their long-standing work in data and AI strategy, Hofmann and Kruhse-Lehtonen offer practical insights into strategy, governance, and the evolving “mindware” required to make agentic AI deliver real value. The episode also highlights their forthcoming HDSR article, “ The Agent-Centric Enterprise: Why 2–10x Productivity Gains Demand Radical Workflow Redesign, ” and their joint online course with the Harvard Data Science Initiative, Agentic AI: Contextualized and Applied , which focuses on applying agentic systems responsibly in real organizational settings. Our guests: Dirk Hofman is the co-founder DAIN Studios and CEO of DAIN Studios Germany Ulla Kruhse-Lehtonen is the co-founder of DAIN Studies and CEO of DAIN Studies Finland
Highlighted moments
“it's not output, it's outcome. So you really need to think of what makes you and your business or you as a person, what makes you successful? What is what you want to reach? What's the bottom line at the end? And then think about how you get there.”
“I would change the word artificial actually to augmented in that sense, because also I think what we highlighted before is the, the superpower comes if we combine, you know, our human intuition, our human contextuality, our human impreciseness and combine it with the intelligent power of those models and algorithms.”
Transcript
Introduction to Egenic AI
0:00Hello, and welcome to the Harvard Data Science Review podcast. I'm Liberty Vittert Capito, the feature editor of the Harvard Data Science Review, and I'm joined by my co-host and editor-in-chief, Xiaomei.
0:14Egenic AI is moving fast, from systems that assist us to systems that develop ideas and make decisions. But what does this mean for our work, and where is it taking us next? Today, we're diving into Egenic AI with two people who are helping define the field, Dirk Hoffman and Ulla Cruz. They are the co-founders and co-CEOs of Dean Studios. They have written extensively on the topic for the Harvard Data Science Review, and together with the Harvard Data Science Initiative, they've created a two-and-a-half-week online course,
0:47Egenic AI, Contextualized and Applied. In this conversation, we'll unpack what makes AI truly Egenic, and how to apply it responsibly where it adds real value, and how to work effectively alongside these systems. Whether you're building these systems, deploying them in your own organization, or using them day-to-day, this episode is for you.
Guest Introduction
1:11Well, thank you, Ulla and Dirk, for joining us. So I'd like to start by asking, first tell us a little bit about your company, Dane, and particularly explaining the name, because I always find the names fascinating, and just give our audience, which is mostly data scientists, a broad sense of the business you're in. Well, thank you, Shirley. It's great to be here. We got the idea about Dane, and Dane stands for Data, AI, and Insights.
1:42At some point in late 2015. Initially, it's three founders, so we got two Finns and one German, and we got to know each other at Nokia, the mobile phone Nokia company back in the day, which was now, in hindsight, actually doing very, very interesting things in AI, and really, truly big data with maps, and with supply chain, and all these services, applications that we used. So that was the start, and we were looking for really making an impact on how companies
2:18transform themselves using data and AI, and that's how we got together and how we got started. And over these 10 years, we have now grown. So we have a team of data scientists, data engineers, strategists, software engineers, BI developers, and basically, we try to think of ourselves as an end-to-end consultancy where we offer both the strategic help and then also do implementations as well.
Data and AI Strategy
2:48Back in 2020, you two published an article in Harvard Data Science Review titled, How to Define and Execute Your Data and AI Strategy. Now, five years may not seem long, but in the space of AI, that's like ancient. And so the question I have for you is, what were the core arguments you were making then, and what are the concerns, opportunities that felt most urgent back then? At the time, what we wanted to highlight that you need this structure to really translate
3:22your business strategy into a systematic approach, that it's understood that it's not only driven by the technology and advancement of the technology. This is also why the structure still holds, because it's timeless. And at the time, you could say we talk about an AI strategy. And I think while companies were very used to do business strategies, it was not clear that you also need to do that for AI and data. And when we now look at companies, so five years later, you see some of the companies,
3:52they have done almost every year an update of their strategy. So as you have your finance sector, your marketing sector. So now AI and data science is an incremental part of the DNA of a company. And I think five years ago, this was still something new and not that obvious. Now, of course, many companies went that route. But also, as just said, I think it's still important to see that this is not a one-off exercise. It's an ongoing exercise.
4:24I wanted to dive a little bit into this new article that's coming up for you all in the Harvard Data Science Review for this January issue. One thing that we have seen is that hindsight is 20-20. And when people look back and they go, oh, well, we knew this or we didn't know this. Looking back over the last five years since you all wrote your article in 2020, but back to 10 years ago when you all started your company, what assumptions have you all gotten right and what have you gotten wrong?
4:54This is a very good question. And of course, always good to reflect. I think, of course, in some areas, we anticipated that companies will accelerate faster in that sense, kind of more taking that advantage of it. And of course, you could say maybe learning and maybe underestimating how hard it is for companies to change the way how they do things. We both are more on the optimistic side. So we always see more opportunities. But of course, that might not be always the case for companies. For us, it was clear that the future, and that's also you could see a driver of the article
5:28now, is you will not be having a sustainable business if you're not leveraging the potential of data and AI. The most successful companies will have a hard time to tell you how many data or AI people they have in their organization, because it's an obvious skill across the whole team and so on. And this is something for them is a prerequisite. Yeah. The world is going to the direction where the lines between, say, business and technology are blurring. So if it used to be that that business was that the brain and the IT people were the legs
6:04that were just implementing, that's changing now because it's so much easier also with the type coding and with all the apps for business people. If they have a vision, if they know where they're going to use the tools and express themselves and the vision. And then, of course, it needs to be scaled. It isn't enterprise ready if we here are doing our own work. But you can get done so much more than before, which will be a fundamental change in companies.
6:35Like still 2020, we thought more that, for example, data scientists, that it makes sense to have a central unit where you are, to some extent, outsourcing these skills. But now I think that these lines are getting blurrier and blurrier. So we cannot separate technology, data, AI from business anymore. So it's evolving everywhere. And that's also what we're saying with the agents and the agentic AI, that we will all
7:08be really working side by side with AI agents in our everyday work.
Defining Agentic AI
7:15How do you define agentic AI in practical terms? Because, you know, obviously there are many, many takes on that. And fundamentally, why do you see that as, using Dirk, your term, it's a transformative shift, rather than just another incremental advance in automation, for example. From a definition, this is, of course, I think an interesting one. And maybe when we talk about agentic AI, first of all, I think we refer to workflows and processes and so on. So it's not a single function and task, but it's the combination of agents.
7:49And I think, for example, in the discussion with leadership teams is think about kind of what makes a good coworker for you. So a good coworker is somebody with a lot of experience. Experience refers to memory. That means you have the access to a lot of information, learnings from the past, which you can leverage. Same time, experience requires also the skills. That means skills comes from your education, your ability to, for example, do calculations, summarizing things and so on.
8:19The third element, and that is especially from an agentic perspective, is that for you as a colleague, it's clear what you are expected to provide as an input, and it's clear what you also expected to deliver to others. So that you kind of, you are embedded into the workflow. And then the last element is, as you could see, in technical terms, we talk about guardrails. As a coworker, you would talk about there are certain rules, you know, how things are done. There are certain rules, how you behave. So agentic AI means it's embedded in the operating system of companies.
8:53So there will be agents engaging with humans and vice versa. And I think that also means we need to learn, and that's the upskilling part on the human side. How do we interact with such solutions? How do we create the context needed? How do we work in collaboration? At the same time, of course, it also provides very strong requirements on how you need to design the agents in such an environment. So how you need to provide the information that we, as human, can take the right decisions
9:25when decisions are needed or expected from us along the process. You know, when I teach some of my classes or I talk to some of the professionals that I teach, you know, I say, you know, how many of you all use AI or whose company, you know, someone from up top said you need to use AI. Pretty much all of them raise their hands. And then I say, how many of you guys is it useful for? And it's rare to have one hand go up because, you know, it's just, it's so hard for companies to really implement this. So where is it that you see a Genic AI making, you know, sort of a real tangible difference
9:59in organizations where everybody really understands and believes in its adoption, other, whether it's through your own work or sort of more broadly. And if you could also address what this issue is, where expectations are sort of outpacing what's actually happening on the ground. Yeah, I think, I think we very much, one of the most important things, and maybe it's partially reason for excitement, but also then the disappointment is that at the end, it is about that you're clear what, what makes the difference from an outcome.
10:31What I mean with that, for example, company got very excited initially about, I can generate now many, many copy texts for a campaign. I can now create hundreds social posts within minutes. So the, the, the effort is very low. So that's initially very exciting, but then the disappointment comes because actually it's not about if you can now generate a hundred posts. Your aim is to convert, for example, prospects, convince people about your products and so on. So that means you need to be very clear about the outcome.
11:03So this is also the starting point before going into what is the solution you want to use is, are you clear what counts for you? And these tools are now very much fascinating because they lure you in trying it out. You get the result. First result looks very promising. So that's why everybody has tried it out and, and, and accessibility was never that low as, as today. But after a while it wears out a bit because then people realize actually nothing has changed in my daily business. I still do at the end, the same things as before.
11:34And therefore it is so important that you really go one step back, think about the outcome. And that's also what we, what we emphasize and highlight in the, in the course is that it's not output, it's outcome. So you really need to think of what makes you and your business or you as a person, what makes you successful? What is what you want to reach? What's the bottom line at the end? And then think about how you get there. And this is the nice opportunity that now those tools, they provide new ways of doing
12:05things. I think coding is a perfect example that where before it has taken weeks to get the first version of a product or kind of a landing page. Now you can do that in minutes or in hours. But it only will be impactful if you know why you're doing a landing page. Otherwise you will have a lot of landing pages, but nothing will change. And then you got back to this frustration. I think that's also why I'm always get excited when, when Jolly, when you talk about this mind where, because for me, the current phase is the most intellectually, the most exciting
12:36phase in my, in my life in that sense, because it forced you really to rethink how you do things. I would say it's very demanding and so on, because we are so used to do things as we have done over the years. And of course, has also been proven in our career that we have done certain things right. So very demanding to figuring out, okay, where do I focus on? What really makes it relevant for me? Well, I certainly share that sentiment. I, you know, have done many things over the years. I do find I'm expanding my own mind where, and I particularly want to talk a little bit about
13:10this course we have been offering together for HDSR itself is really something I certainly would not have anticipated even a year ago, that we'll be teaching a course on agentic AI. Of course, a year ago, we don't probably even know the term that much yet. I'm looking at the title from the, you know, Forbes magazine, right? It had this title called Three Courses to Master AI Agent and Boost Your Salary in 2026. And our course is listed as number one.
13:41The title is Agentic AI Contextualized and Applied. Now, the last thing we want to do is any hype, as we all understand. So there got to be something real here. So can you share what was your design principle? How do you make sure the course is accessible, but without oversimplifying such a fast moving and, you know, frankly, very technical topic? Well, I think it's a combination. The course teaches in just two and a half weeks, as you say, some good frameworks like
14:14this agent framework, as we call it. So you're immediately from the beginning starting to think about your own use cases, your own workflows, what you could do better. So it isn't only that you first listen to a lot of lectures and then you start doing something yourself, but you start the journey right from the beginning. And the course itself uses AI, it's very AI-based. So there is a learning platform called Pasci, which was or is developed by NGL, which personalizes
14:49the learning experience for every participant. So it helps you, it guides you along your way when you're doing your exercises, when you're designing your workflows. It asks just the right questions. You can discuss with it like a friend. So it's a very, very different and new and effective learning experience. And then I believe these live lectures that we're having, so which with all of us and other faculty are then adding interest to the topics and there are some case studies, participants
15:24can ask questions. And the community aspect is also important. So there are people, very high profile, busy, C-level people from large enterprises, and they have a chance to interact with each other and exchange ideas. You have very strong peer support in that course. And in fact, many have expressed the wish that they can continue, which is also now becoming available after the course, continue this interaction with both the tool, the personalized
16:01tool, Pasci, as well as with each other. I think my biggest question and what I know that so many educators are struggling with right now is how to keep their courses current because things are changing so quickly. It's, you know, I almost sometimes feel like I'm learning right along with my students with how quick things are happening. You know, I remember when ChatGPT came out, you know, I was, I was the weekend before my classes, I was trying to figure out how everything was working and moving so that I could teach
16:33it on Monday. How do you all keep up with that? How do you keep everything that you're doing current? What's your sort of, what's your mode of doing that? Yeah, you go to sleep and in the morning, there's another, another solution in the market, but, but a bit along the line, what Ula already said, and also what we highlight in the course that, that you look a bit beyond what is the technology. So not about the features, but what is the function and so on, for example, what it makes and what is required to use it in the best way. And that's a bit with the, with the framework like agent and the systematic.
17:07So I would, I would say one thing is having a clear systematic, what, how you, how you structure, you know, the problem you want to solve this, how you structure to identify what is relevant, because having a structure in mind, it helps you put things into, this is something relevant and it should change what you should learn and what you should know, or is it something which, which is in the same bucket than maybe five other news you have heard before, like feeling, feeling paranoid on the one hand side that something new is changing and you
17:38need to catch up at the same time, also being a bit, you know, Zen feeling like, Hey, yes, this has changed and so on. But bottom line, we still talk about the same. And I think more than, more than ever, it's so important to have academia and then the applied, for example, applied practices, what we do together, because that also helps you to keep identifying the right signals in all the noise, because we have so much noise in what we hear every day. So being able to, to use academia and the structures, the metals behind to, to filter out the right
18:14signals and filter out what really is relevant. So that's also where I see more than ever, it's so important to bring the different disciplines together and, and have this exchange and reflection. So far, we have been talking about agentic AI as this kind of a, you know, human empowering tools, right?
Risks and Concerns of Agentic AI
18:32But as we said, you know, we want to make sure that there's no hype here. There, there's obvious concerns of using agentic AIs. One of the things you will hear people talk about is, well, is there a real risk that we're actually designing systems that quietly shift the decision-making authority away from people? And how does that affect our own, you know, human's decision-making process? You know, we understand the mechanics, we understand the architecture, but we still don't quite fully
19:02understand, even for those of doing data science is how does it become so powerful or sometimes just hallucinating for no reason, right? Do you see any of the dangers of those things? And, and where do you draw a line? And from really a practical perspective, as two of you have been advising lots of companies, right? From practical perspective, how can we be empowered by these tools, but not kind of enslaved, so to speak, by them, right? And, you know, maintain or human's autonomy or decision-making, you know, or thinking, right?
19:40Yeah, I guess in the, in the first place, always ensure that the tools don't take decisions autonomously. I mean, they're able to make recommendations and they're able to reason and so forth. That's, of course, their power, but in the end, if we think of like critical areas such as healthcare or finances and so forth, then to ensure that in the end, somebody is checking and, and then you have those guardrails in place to the extent it's possible.
20:14You, you have a, and like an AI governance model around it, which you have, have defined where the policies and the regulations, the level of autonomy that you allow for, for the agents that may change from a company to company and also the use case. So if you do marketing, marketing isn't as critical if it goes wrong, if it isn't fully targeted versus a decision about a patient's health. So you do need to think critically and also like in some use cases that we have done, even
20:49if they are not super critical industries, but we have decided not to allow AI to do its own coding. So we have first used AI more as a rule base. So like an automation, okay, go do these things that we have defined because if we're not entirely sure that it isn't going to invent something on its own. So, so you're building also things stepwise and, and constantly testing and checking that
21:20you're still in control, but in the end, it comes a bit back to also your, your questions at Liberty about where, where it makes sense to use agents and good, good ways to start. In my opinion, our, our cases where there is a lot of manual work and the automation would really bring, bring efficiency, would be, make everybody happier, would give people more availability to do their job better and focus on, on where people are needed and let in
21:52the way the machines do the machines job. Maybe one, one thing to add is, is also is related to, if you see it kind of agentic AI or AI, it's more like, you know, a bit like the calculator at school and so on are great. Now I don't need to know math. So if you see that as an easy way out to, to get lazy, I think then, then you will run increasingly into problems because then you will lose even more, you know, the oversight and the control and so on. And I think more than ever kind of skills like system thinking, critical thinking will be
22:25fundamental. So actually you could say, well, maybe some of your muscles can loosen up a bit, but you need to strengthen other ones in your body. That will be fundamental. I will see a software developer who then say, this is great. I don't actually need to know any more coding and the, and the basic practical. It will be maybe boosting a bit in the beginning, but it will not be sustainable because you will be eaten up by the complexity and then you will not be able to orientate yourself and, and getting those things solved. And that goes also back to what I said before is being clear what, what you want to achieve.
22:59And that's one of the core skills more than ever is know what you want, know what you need. And now the tools are there, which help you to, to reach that in a better way. But in a way I would say it's rather more intense than less intense than before. And then build in those governance capabilities. So think about who is accountable and what risks are acceptable and who makes decisions. And then there's also all things related to data and security topics.
23:30And so it needs to be in many ways, almost like governance by design. So when you do AI work, you're thinking about not as an afterthought. So how do I govern this? But, but actually from the beginning, how do I build AI governance into, into any of my solutions? So we're going to end on what we, we always do, which is our magic wand question. This is a little bit of a weird one. So it may take you a second. It took me a second. You know, if you could wave your magic wand and if you could change one word in how people
24:06currently think or talk about a genic AI, what would that word be? And I, if you can't think of a word, I'm going to, I'm going to edit it a little bit to say it could be a sentence. I know immediately it's the word automation. People think of AI agents as simply automation like RPA. So we just automate this, we automate that. And that's of course true, but it's also falls a bit short because AI agents really truly can
24:40work autonomously. They can make decisions on their own. They can reason. You can build entire teams. You can do many complex solutions with them. And, and that's, that's something I would like to change. Yeah, I think I can second that one. And maybe my, my, what would be for me, it feels more, we talk about, you know, I would change the word artificial actually to augmented in that sense, because also I think what we highlighted before is the, the superpower comes if we combine, you know, our human intuition,
25:12our human contextuality, our human impreciseness and combine it with the intelligent power of those models and algorithms. I still believe this is unbeatable because I think this together brings so much more dimension into the equation. The combination is super powerful. And I think as Ula said, and then that's also why it's far beyond then automation. It's so much more. Well, thank you to both of you. I really can't agree more, which you just, you know, summarized. And I always tell people that at least the current artificial intelligence, there's nothing
25:46artificial whatsoever. They're all created by humans. They're trained on human data. And, you know, in the future, we don't know. It's hard to predict the future, but so far I can tell it's really not, you know, artificial, but augmentation is great. Humans are always good at creating tools to do things we cannot do, right? The computer itself is a shining example, can calculate things far faster than anybody can. If you want to learn more, please read the article by Ula and Dirk coming out of the next issue,
26:21which is January issue of HDSR. And the preprint is already online with the title, Agenic-centric enterprise, why 2 to 10 times productivity gains demands radical workflow redesign. Thank you for listening to this month's episode of the Harvard Data Science Review podcast. Check out our show notes for links to Dirk and Ella's HDSR journal articles and the registration for their course, Agenic AI Contextualized and Applied.
26:53The next two and a half week session starts on February 17th. To stay updated with all things HDSR, you can visit our website at hdsr.mitpress.mit.edu or follow us on Twitter and Instagram at the HDSR. A very special thanks to our executive producer, Rebecca McLeod, and producers Tina Tobey-Mack and Aaron Kieswetter. If you liked this episode, please leave us a review on Spotify, Apple, or wherever you get your podcasts. This has been the Harvard Data Science Review.
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